RLD / Orange Book Comparator
Follow reference-listed drugs for label, patent, and exclusivity changes without checking the FDA site by hand.
The problem it solves
Reference-listed drug data (patents, exclusivity, label changes) does update on the FDA's own site, but nobody's job is to check it daily — so a generics team finds out about a relevant change only once it's already old news.
How it works
- 1Add the reference-listed drugs your generic programs actually track.
- 2A scheduled refresh pulls current data directly from openFDA and compares it against what was last recorded.
- 3Any real difference is logged as a change event, so the team reviews what changed instead of re-reading the whole record.
Who it’s for
Regulatory affairs staff at generics manufacturers tracking reference-listed drugs.
Is this the same data as the FDA's own Orange Book?
Yes — it's sourced live from openFDA, the FDA's own public API. This tool doesn't hold private data; it watches the public record for you and flags what changed. A no-login version is available to try without an account.